You could also gain weight, depending on what happens first and the type of hepatic disease you’re suffering. If you’re gaining weight, it is likely because of liquid retention in the body. The liver synthesizes one of the most critical proteins in the blood. It is called albumin, and it is responsible for many functions in the body. One of them is regulating the fluid balance inside and outside of the blood vessels. When albumin levels are low in the blood due to liver damage, liquid leaks out of the blood vessels and stays in the extracellular space. In some cases, patients get a big and round belly, but not because of fatty tissue. It is called ascites, and it is a massive accumulation of liquid in the abdominal cavity.